Aveneu Park, Starling, Australia

Cardiovascular , etc With the current lifestyle

Cardiovascular diseases belong to a category of diseases in which detrimental effects occur on heart and blood vessels. Across the globe , these are the most recurrent cause of human mortality. In India they are believed to account for about a quarter percent of demises. A notable disease affecting the myocardium is myocardial ischemia. In ischemia there is a barrier to blood flow in arteries due to plaque hoarding and appearance if clots. . This lowers the quantity of oxygen delivered to the cardiac tissue. The outcome is the wounding of  myocardial tissue in the state of Ischemic hypoxia.  Various alterations are commenced in the cardiac tissue as a consequence of ischemia.
These involve morphological changes in terms of size of the cardiac tissue, enzymatic changes that pertain to the level of myocardium associated enzymes.
Hemodynamic changes of decline in blood pressure, heart rate and ejection fraction 
are also an aftermath of ischemia.
Arrhythmias may accompany cases of ischemia and some may be fatal.
The net result of these changes is the dysfunctioning of cardiac tissue contributing to heart complications such as heart attack , heart failure , etc
With the current lifestyle trend , incidence of ischemia and other ischemia related complications is on a rise.
Intensive research is being undertaken in hopes of finding cardioprotective agents that have significant reversal effects on ischemia.
Recently , the cardioprotective potential of oxytocin has been identified. 
Oxytocin synthesized in hypothalamus and showing effects of uterine contraction during labor , milk ejection during lactation was also found to be synthesized in heart.
This possibility of cardiovascular role of oxytocin is implied by this.
The delivery of oxytocin to body effects the blood pressure, heart rate, etc..
Oxytocin enhances the production of Atrial natriuretic peptide and Nitric oxide which will decrease the work load on the heart by decreasing the preload and increasing the blood flow to the ischemic heart.
Hemodynamics changes were recorded in pregnant women administered with oxytocin and undergoing Caesarean section.
The present study tests the hypothesis that oxytocin exerts cardioprotective effects against ischemia.


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