The patentee Henan Elraz of the “Insect Repellent Formulations” stated thatthe present invention provides an insect repellent aqueous formulation comprising of the following ingredients: a combination of at least two essential oils, citrus peel tincture, and vinegar. The novel combination of ingredients in the insect repellent formulation of the invention creates a substantially enhanced effect compared to that obtained by using each of the ingredients separately. The formulation of the invention uniquely combines active ingredients possessing repelling effects on insects (e. g. ssential oils, vinegar) with an alcoholic extract of citrus peel which allows effective dispersion of the formulation in the air surrounding the person using the formulation, as well as stabilization.
In a preferred embodiment the formulation further comprises an emulsifier. In one embodiment the essential oils are selected from the group consisting of lemongrass oil, citronella oil, eucalyptus oil, tea tree oil, lavender oil, geranium oil, clove oil, Cajeput oil and Lemon balm oil. The concentration (volume/volume) of each of the essential oils in the formulation ranges between about 0. % and about 3%, preferably between about 0. 5% and about 2%. In one embodiment, the citrus tincture is mandarin tincture. The concentration (volume/volume) of the citrus tincture in the formulation ranges between about 0. 1% and about 1%, preferably about 0. 5%. In one embodiment the vinegar is apple vinegar in a concentration ranging between l%-10%, preferably between 4% and 6%, and more preferably about 5%.
In one embodiment, the emulsifier is Tween 20. The concentration (volume/volume) of the emulsifier in the formulation ranges between about 0. % and about 1%, preferably about 0. 5%. In a preferred embodiment the insect repellent formulation of the invention comprises a combination of lemongrass oil, citronella oil, tea tree oil, lavender oil, mandarin peel tincture, apple vinegar and Tween 20. In one embodiment, the formulation of the invention further comprises additional ingredients having insect repelling activity. By another aspect, the present invention provides an applicator suitable for administration of the formulation of the invention.
In one embodiment, the applicator is selected from the group consisting of a pump dispenser suitable for spraying the formulation onto the skin, an applicator stick, or napkins soaked with the formulation suitable for rubbing the formulation on the skin and a sticker soaked with the formulation suitable for attachment onto the skin. In another aspect, the present invention provides a method for protecting individuals from being stung by insects comprising applying the formulation of the invention using an applicator as described above.
In another aspect, the present invention provides a method of preparing an insect repellent aqueous formulation comprising: a. Mixing a combination of essential oils with an emulsifier and citrus tincture; b. Adding to the mixture water at a temperature of about 4O0C and vinegar, wherein the final concentration (v/v) of water is 90% and the final concentration of vinegar (v/v) is 5%; c. Mixing for about 2 hours at ambient temperatures using a mechanical stirrer; and d. Allowing the mixture to rest prior to administration; the resting period may be for about 24 to 72 hours, preferably for about 48 hours.
In the embodiment preferred by the researchers, which is the combination of citronella oil, lavender oil, tea tree oil, lemongrass oil, citrus peel tincture, tween 20 (polysorbate 20) and water which was then mixed for 2 hours, using a mechanical stirrer, with distilled water (heated to 40°C) and natural apple vinegar, produced the following result when field tests were conducted by the inventor: According to the results of the control (number of landing mosquitoes on the unattended arms) the formulation was examined with ready to bite mosquito females.
The formulation showed high efficiency repelling mosquitoes for as long as four hours. No repellency reduction was observed during the last inspection, four hours after the repellent was spread on the arms, as the formulation remained 100% repellent. Accordingly, it is highly reasonable that the formulation repel mosquitoes for a longer period than 4 hours. The inspected mosquito species (Culexpipiens and Culexunivittatus) are of the most common human biters mosquitoes in Israel and may transfer pathogens like West Nile Virus.
The importance of this study on these species is high due to their high levels of distribution and their nuisance and public health hazard effects. Table number 2: The experimental report of the formulation. The table demonstrates the repellent efficiency protecting the arms of 7 different volunteers from the contact of about 60 Culexpipiens and Culexunivittatus mosquito females. Table 1 Multi-component repellent formulation Table 2: Experimental Result of the Formulation The business targets the following establishments as their main product outlets * Mercury Drugstore South Star Drug * LCC Department Store * Metro Gaisano * Save More * And other leading supermarkets and department stores. * Department of Health The proposed business aims to produce an insect repellent that has a unique formula that uses natural essential oils. This feature of the product makes it suitable for consumers of all ages. As compared to the synthetic repellents that are at the moment dominant in the market, it has no side effects and also guarantees protection for a long period of time.
The product will come in different scent and volume. As to the packaging, it can be in a bottle that allows full coverage application on the skin and in a pump spray that allows easy application. Definition of terms INSECT REPELLENT FORMULATION- a composition which repels insects. Repellence may be determined by either the inhibition of insect approach, landing on a target or stinging. ESSENTIAL OIL- any concentrated, hydrophobic liquid containing volatile aroma compounds from plants.
Essential oils in the context of the invention may include, without being limited thereto, an essential oil selected from lemongrass oil, citronella oil, eucalyptus oil, tea tree oil, lavender oil, spearmint oil, geranium oil, rosemary oil, Lemon balm oil, peppermint oil, pine needle oil, lavandin oil, cinnamon oil, clove oil, thyme oil, wintergreen oil, cedar oil, lemon oil, grapefruit oil, mandarin oil, tangerine oil, orange oil, citrus oil, lime oil, coriander oil, pomegranate oil, soybean oil, cajeput oil, walnut oil, peanut oil, corn oil, canola oil, sunflower oil, sesame oil, linseed oil, safflower oil, olive oil, etc.
CITRUS TINCTURE- is an alcoholic extract of citrus peel. As used herein, Citrus refers to a genus of fruit comprising, but not limited to, orange, bergamot, grapefruit, lemon, lime and mandarin. “Vinegar” in the context of the invention refers to a sour, aqueous liquid, generally containing about 4%-8% acetic acid, obtained by the acetic fermentation of dilute, aqueous alcohol solutions, e. g. by bacterial fermentation of wine, apple cider or fruit juice.
Active Ingredient- means a compound which possesses an insect repelling activity when applied to a subject’s skin, e. g. turpentine, pennyroyal. EMULSIFIER- (also known as an “emulgent”) a substance which stabilizes an emulsion, frequently a surfactant. Non limiting examples include Tween and paraffin oil. AQUEOUS FORMULATION- means a water-based composition, wherein the major component of the composition, by volume, is water.